Visual analysis of drug research and development based on artificial intelligence
The iteration of artificial intelligence (AI) technology provides new opportunities for drug research and experimental development. In recent years, AI-based drug research has continuously made new progress and has garnered widespread attention. This study retrieved data from a total of 23,096 paper...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2024-12-01
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| Series: | Journal of Holistic Integrative Pharmacy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2707368824000657 |
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| _version_ | 1846099789066797056 |
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| author | Wei Wei Chao Song Changxing Qi Xin Zhang Xiaoyi Zhang Run Pu Yi Ao |
| author_facet | Wei Wei Chao Song Changxing Qi Xin Zhang Xiaoyi Zhang Run Pu Yi Ao |
| author_sort | Wei Wei |
| collection | DOAJ |
| description | The iteration of artificial intelligence (AI) technology provides new opportunities for drug research and experimental development. In recent years, AI-based drug research has continuously made new progress and has garnered widespread attention. This study retrieved data from a total of 23,096 papers in AI-based drug research and development from the Web of Science up to May 14, 2024, and conducted bibliometric analysis using VOSviewer software. The results indicated that the AI-based drug research and development is a globally recognized hotspot, and the United States holds a certain authority in this field, while China ranks second in total publication output. The integration of AI technology with drug development primarily involves four stages: drug discovery, preclinical research, clinical trials, and drug manufacturing. So, AI technology has been applied throughout the entire process of drug development. AI-based virtual drug screening and structure-activity relationship analysis started early, while graph neural networks, pre-trained models (Transformer), interpretable AI technology, ChatGPT, and large language models were significantly highlighted in the last 3 years. Moreover, since 2020, AI-based drug repurposing, molecular dynamics simulation, 3D printing, and drug delivery system design have emerged as research hotspots and have been mainly applied to, particularly, on COVID-19, disease prognosis, liver cancer, lung cancer, and immunotherapy. |
| format | Article |
| id | doaj-art-377d2a2dd5fc4eedb1ac56c7c8b28b70 |
| institution | Kabale University |
| issn | 2707-3688 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Holistic Integrative Pharmacy |
| spelling | doaj-art-377d2a2dd5fc4eedb1ac56c7c8b28b702024-12-31T04:13:29ZengKeAi Communications Co., Ltd.Journal of Holistic Integrative Pharmacy2707-36882024-12-0154323332Visual analysis of drug research and development based on artificial intelligenceWei Wei0Chao Song1Changxing Qi2Xin Zhang3Xiaoyi Zhang4Run Pu5Yi Ao6China National Center for Biotechnology Development, Beijing, 100039, ChinaChina National Center for Biotechnology Development, Beijing, 100039, China; Vanke School of Public Health, Tsinghua University, Beijing, 100084, ChinaChina National Center for Biotechnology Development, Beijing, 100039, China; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, ChinaChina National Center for Biotechnology Development, Beijing, 100039, ChinaNew Technology Center of the Ministry of Science and Technology, Beijing, 100039, ChinaChina National Center for Biotechnology Development, Beijing, 100039, ChinaChina National Center for Biotechnology Development, Beijing, 100039, China; Corresponding author.The iteration of artificial intelligence (AI) technology provides new opportunities for drug research and experimental development. In recent years, AI-based drug research has continuously made new progress and has garnered widespread attention. This study retrieved data from a total of 23,096 papers in AI-based drug research and development from the Web of Science up to May 14, 2024, and conducted bibliometric analysis using VOSviewer software. The results indicated that the AI-based drug research and development is a globally recognized hotspot, and the United States holds a certain authority in this field, while China ranks second in total publication output. The integration of AI technology with drug development primarily involves four stages: drug discovery, preclinical research, clinical trials, and drug manufacturing. So, AI technology has been applied throughout the entire process of drug development. AI-based virtual drug screening and structure-activity relationship analysis started early, while graph neural networks, pre-trained models (Transformer), interpretable AI technology, ChatGPT, and large language models were significantly highlighted in the last 3 years. Moreover, since 2020, AI-based drug repurposing, molecular dynamics simulation, 3D printing, and drug delivery system design have emerged as research hotspots and have been mainly applied to, particularly, on COVID-19, disease prognosis, liver cancer, lung cancer, and immunotherapy.http://www.sciencedirect.com/science/article/pii/S2707368824000657Visual analysisDrug research and developmentArtificial intelligenceVOSviewer softwareBibliometrics |
| spellingShingle | Wei Wei Chao Song Changxing Qi Xin Zhang Xiaoyi Zhang Run Pu Yi Ao Visual analysis of drug research and development based on artificial intelligence Journal of Holistic Integrative Pharmacy Visual analysis Drug research and development Artificial intelligence VOSviewer software Bibliometrics |
| title | Visual analysis of drug research and development based on artificial intelligence |
| title_full | Visual analysis of drug research and development based on artificial intelligence |
| title_fullStr | Visual analysis of drug research and development based on artificial intelligence |
| title_full_unstemmed | Visual analysis of drug research and development based on artificial intelligence |
| title_short | Visual analysis of drug research and development based on artificial intelligence |
| title_sort | visual analysis of drug research and development based on artificial intelligence |
| topic | Visual analysis Drug research and development Artificial intelligence VOSviewer software Bibliometrics |
| url | http://www.sciencedirect.com/science/article/pii/S2707368824000657 |
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