Predict the degree of secondary structures of the encoding sequences in DNA storage by deep learning model

Abstract DNA storage has been widely considered as a promising alternative for exponentially growing data. However, the inherent complex secondary structures severely compromise the processes of synthesis, PCR amplification, and sequencing, interfering with reliable information recovery. In large-sc...

Full description

Saved in:
Bibliographic Details
Main Authors: Wanmin Lin, Ling Chu, Xiangyu Yao, Zhihua Chen, Peng Xu, Wenbin Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-05717-3
Tags: Add Tag
No Tags, Be the first to tag this record!