FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification of EPRS

FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification of EPRS

Abstract Background Cardiac fibrosis is common in myocardial infarction (MI), leading to progressive cardiac dysfunction. Studies suggested that the abnormal N 6-methyladenosine (m6A) modification induced by fat mass and obesity protein (FTO) is vital in MI. However, the effects of FTO on post-infar...

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Bibliographic Details
Main Authors: Jian Wang, Yanyan Li, Lijie Deng, Yafang Zha, Song Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Medicine
Subjects:
N6-methyladenosine (m6A)
FTO
EPRS
Cardiac fibrosis
Online Access:https://doi.org/10.1186/s10020-024-00985-7
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https://doi.org/10.1186/s10020-024-00985-7

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