Activity of LpxC inhibitors on carbapenemase-producing Citrobacter spp. clinical isolates

ABSTRACT: Objective: Citrobacter spp. are commonly found in the human intestine and can cause antibiotic-resistant infections. Inhibitors of LpxC, an enzyme involved in the synthesis of lipid A, have demonstrated potent activity against multiple Gram-negative species, but their activity in Citrobac...

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Bibliographic Details
Main Authors: Víctor Vinuesa, Raquel Cruces, Javier E. Cañada-García, Jesús Oteo-Iglesias, Andrés Corral-Lugo, Michael J. McConnell
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Global Antimicrobial Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S221371652500178X
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