Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study
Background: This study aims to identify early detection of precancerous lesions amongst high-risk individuals (motor park workers). Though anecdotal evidence suggests they are high users of alcohol, marijuana, and cigarette smoking which are prominent risk factors for the occurrence of oral cancers...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024002747 |
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| author | Olawale Olatunbosun Adamson Olufemi Erinoso Remilekun Oluwakuyide Abiodun Amao Olajumoke Effiom Olalekan Micah Gbotolorun |
| author_facet | Olawale Olatunbosun Adamson Olufemi Erinoso Remilekun Oluwakuyide Abiodun Amao Olajumoke Effiom Olalekan Micah Gbotolorun |
| author_sort | Olawale Olatunbosun Adamson |
| collection | DOAJ |
| description | Background: This study aims to identify early detection of precancerous lesions amongst high-risk individuals (motor park workers). Though anecdotal evidence suggests they are high users of alcohol, marijuana, and cigarette smoking which are prominent risk factors for the occurrence of oral cancers the occurrence of precancerous lesions in this group has not been determined. Method: This was a prospective cross-sectional study of a target population of motor park workers (40 years and above). Participants were selected from motor parks in Lagos. All participants had an examination of oral mucosa done for pre-cancerous or cancerous lesions. All suspected mucosa were stained with toluidine blue. All positively stained mucosa were repeated after 1 week for confirmation blue for suspicious cases. Positive cases were biopsied and histology was determined. Result: A total of 453 participants completed the survey. The mean age of participants was 39.4 years (SD: 12.5), 52.8 % were male, while 47.2 % were female. A majority of ever and current smokers did not have oral ulcers, and all the participants with oral ulcers did not indicate a history of smoking. a history of ever-smoking was significantly associated with higher odds of oral lesions in both bivariate (OR: 4.58; 95 % CI: 2.04,10.29; p:<0.001) and multivariate models (OR:2.76). Conclusion: Smoking was significantly associated with oral pre-cancerous lesions in this study. |
| format | Article |
| id | doaj-art-369c658d178c490dba53620ca143a5b7 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-369c658d178c490dba53620ca143a5b72025-01-09T06:16:13ZengElsevierOral Oncology Reports2772-90602024-06-0110100428Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based studyOlawale Olatunbosun Adamson0Olufemi Erinoso1Remilekun Oluwakuyide2Abiodun Amao3Olajumoke Effiom4Olalekan Micah Gbotolorun5Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, College of Medicine, University of Lagos, Nigeria; Corresponding author. Department of Oral and Maxillofacial Surgery, Lagos University Teaching Hospital (LUTH), Idi-Araba, Surulere, Lagos, Nigeria.Department of Oral and Maxillofacial Surgery, Lagos State University Teaching Hospital, Ikeja, NigeriaDepartment of Oral Pathology, Lagos Island General Hospital, Lagos, NigeriaDepartment of Oral and Maxillofacial Surgery, Federal Medical Center, Abeoukuta, Ogun, NigeriaDepartment of Oral Maxillofacial Pathology/Biology, Faculty of Dental Sciences, College of Medicine, University of Lagos, NigeriaDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, College of Medicine, University of Lagos, NigeriaBackground: This study aims to identify early detection of precancerous lesions amongst high-risk individuals (motor park workers). Though anecdotal evidence suggests they are high users of alcohol, marijuana, and cigarette smoking which are prominent risk factors for the occurrence of oral cancers the occurrence of precancerous lesions in this group has not been determined. Method: This was a prospective cross-sectional study of a target population of motor park workers (40 years and above). Participants were selected from motor parks in Lagos. All participants had an examination of oral mucosa done for pre-cancerous or cancerous lesions. All suspected mucosa were stained with toluidine blue. All positively stained mucosa were repeated after 1 week for confirmation blue for suspicious cases. Positive cases were biopsied and histology was determined. Result: A total of 453 participants completed the survey. The mean age of participants was 39.4 years (SD: 12.5), 52.8 % were male, while 47.2 % were female. A majority of ever and current smokers did not have oral ulcers, and all the participants with oral ulcers did not indicate a history of smoking. a history of ever-smoking was significantly associated with higher odds of oral lesions in both bivariate (OR: 4.58; 95 % CI: 2.04,10.29; p:<0.001) and multivariate models (OR:2.76). Conclusion: Smoking was significantly associated with oral pre-cancerous lesions in this study.http://www.sciencedirect.com/science/article/pii/S2772906024002747Oral ulcerPre-cancerous lesionsOral cancer |
| spellingShingle | Olawale Olatunbosun Adamson Olufemi Erinoso Remilekun Oluwakuyide Abiodun Amao Olajumoke Effiom Olalekan Micah Gbotolorun Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study Oral Oncology Reports Oral ulcer Pre-cancerous lesions Oral cancer |
| title | Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study |
| title_full | Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study |
| title_fullStr | Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study |
| title_full_unstemmed | Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study |
| title_short | Association between non-healing precancerous oral lesions and ulcers with tobacco smoking: A population-based study |
| title_sort | association between non healing precancerous oral lesions and ulcers with tobacco smoking a population based study |
| topic | Oral ulcer Pre-cancerous lesions Oral cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024002747 |
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