Macrophage to neuron communication via extracellular vesicles in neuropathic pain conditions

Macrophage to neuron communication via extracellular vesicles in neuropathic pain conditions

Neuropathic pain following peripheral nerve injury results from maladaptive changes in neurons and immune cells contribution to mechanisms underlying chronic pain. Specifically, in dorsal root ganglia (DRG), sensory neuron cell bodies release extracellular vesicles (EVs) which promote pro-inflammato...

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Bibliographic Details
Main Authors: Francesca Picco, Lynda Zeboudj, Silvia Oggero, Vincenzo Prato, Thomas Burgoyne, Nikita Gamper, Marzia Malcangio
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Neuropathic pain
DRG neurons
Macrophages
Extracellular vesicles
microRNAs
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024172994
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http://www.sciencedirect.com/science/article/pii/S2405844024172994

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