Labdane Diterpenoids from <i>Leonotis ocymifolia</i> with Selective Cytotoxic Activity Against HCC70 Breast Cancer Cell Line

Labdane Diterpenoids from <i>Leonotis ocymifolia</i> with Selective Cytotoxic Activity Against HCC70 Breast Cancer Cell Line

Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. <i>Leonotis ocymifolia</i> is a shrub widely used in traditional medicine to alleviate cancer-related symptoms. In a search to find safe and efficacious therapeuti...

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Bibliographic Details
Main Authors: Jane Busisiwe Ncongwane, Vuyelwa Jacqueline Tembu, Comfort Mduduzi Nkambule, Douglas Kemboi, Gerda Fouche, Nyeleti Vukea, Jo-Anne de la Mare
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diseases
Subjects:
<i>Leonotis</i>
<i>Leonotis ocymifolia</i>
labdane diterpenoids
<i>bis</i>-spirolabdane
MCF-7
HCC70
Online Access:https://www.mdpi.com/2079-9721/13/5/140
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