Nucleotide degradation and ribose salvage in yeast

Nucleotide degradation and ribose salvage in yeast

Abstract Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosomes into nucleotides. A protein not previously asso...

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Bibliographic Details
Main Authors: Yi‐Fan Xu, Fabien Létisse, Farnaz Absalan, Wenyun Lu, Ekaterina Kuznetsova, Greg Brown, Amy A Caudy, Alexander F Yakunin, James R Broach, Joshua D Rabinowitz
Format: Article
Language:English
Published: Springer Nature 2013-05-01
Series:Molecular Systems Biology
Subjects:
autophagy
mass spectrometry
metabolism
nutrient starvation
Saccharomyces cerevisiae
Online Access:https://doi.org/10.1038/msb.2013.21
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https://doi.org/10.1038/msb.2013.21

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