TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons

TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons

Summary: The vacuolar ATPase (v-ATPase) is essential for acidification of intracellular organelles, including synaptic vesicles. Its activity is controlled by cycles of association and dissociation of the ATP hydrolysis (V1) and proton transport (V0) multi-protein subunits. Mutations in genes coding...

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Bibliographic Details
Main Authors: Sara Pepe, Davide Aprile, Enrico Castroflorio, Antonella Marte, Simone Giubbolini, Samir Hopestone, Anna Parsons, Tânia Soares, Fabio Benfenati, Peter L. Oliver, Anna Fassio
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:iScience
Subjects:
molecular neuroscience
cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224027421
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http://www.sciencedirect.com/science/article/pii/S2589004224027421

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