Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products

Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products

Abstract Microbial genetic circuits are vital for regulating gene expression and synthesizing bioactive compounds. However, assessing their strength and timing, especially in multicellular fungi, remains challenging. Here, an advanced microfluidic platform is combined with a mathematical model enabl...

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Bibliographic Details
Main Authors: Xinran Xu, Yanhong Sun, Anxin Zhang, Sijia Li, Shu Zhang, Sijing Chen, Chunbo Lou, Lei Cai, Yihua Chen, Chunxiong Luo, Wen‐Bing Yin
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
filamentous fungi
gene regulatory circuits
microfluidics
quantification
secondary metabolism
Online Access:https://doi.org/10.1002/advs.202407195
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https://doi.org/10.1002/advs.202407195

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