Evaluation of Quinazolin-2,4-Dione Derivatives as Promising Antibacterial Agents: Synthesis, In Vitro, In Silico ADMET and Molecular Docking Approaches

Evaluation of Quinazolin-2,4-Dione Derivatives as Promising Antibacterial Agents: Synthesis, In Vitro, In Silico ADMET and Molecular Docking Approaches

A series of new quinazolin-2,4-dione derivatives incorporating amide/eight-membered nitrogen-heterocycles <b>2a</b>–<b>c</b>, in addition, acylthiourea/amide/dithiolan-4-one and/or phenylthiazolidin-4-one <b>3a</b>–<b>d</b> and <b>4a</b>–&l...

Full description

Saved in:
Bibliographic Details
Main Authors: Aboubakr H. Abdelmonsef, Mohamed El-Naggar, Amal O. A. Ibrahim, Asmaa S. Abdelgeliel, Ihsan A. Shehadi, Ahmed M. Mosallam, Ahmed Khodairy
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
quinazolin-2,4-dione
eight-membered nitrogen-heterocycles
dithiolan-4-one
phenyl-thiazolidin-4-one
antibacterial assessment
molecular docking
Online Access:https://www.mdpi.com/1420-3049/29/23/5529
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/29/23/5529

Similar Items