Ursolic acid attenuates obesity-related metabolic dysfunction via modulation of peroxisome proliferator activated receptor-gamma in male Wistar rats fed with high-carbohydrate high-fat diet

Ursolic acid attenuates obesity-related metabolic dysfunction via modulation of peroxisome proliferator activated receptor-gamma in male Wistar rats fed with high-carbohydrate high-fat diet

Abstract Background The risk factors of metabolic syndrome (MS) precedes the development of cardiovascular disease and type 2 diabetes and are largely triggered by high-carbohydrate high-fat diet (HCHFD) and sedentary lifestyle. The development of these risk factors is connected to persistent low-gr...

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Bibliographic Details
Main Authors: Oluwatosin O. Omodara, Mohammed U. Kawu, Ibrahim G. Bako, Daniel H. Mhya, Theophilus T. Dawus
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Ursolic acid
Metabolic syndrome
Obesity
High-carbohydrate high-fat diet
20 weeks
Insulin resistance
Online Access:https://doi.org/10.1186/s43088-024-00565-y
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