17β estradiol activates autophagy and attenuates homocysteine mediated inflammation in endothelial cells through PI3K AKT MTOR signaling

17β estradiol activates autophagy and attenuates homocysteine mediated inflammation in endothelial cells through PI3K AKT MTOR signaling

Abstract The accumulation of plasma Hcy has been linked to vascular inflammation, which can result in vascular dysfunction. Autophagy has been the subject of extensive research in the context of hypertension-related vascular inflammation injury. As demonstrated in a preceding study, the protective e...

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Bibliographic Details
Main Authors: Tong Yu, Dandan Zhang, Yi Yang, Yu Jiang, Jia Wang, Jing Li, Yannan Zhang, Rong Xie, Xiuqin Hong
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Hypertension
Estrogen
Homocysteine
Autophagy
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-08797-3
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https://doi.org/10.1038/s41598-025-08797-3

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