Synapsin 2a tetramerisation selectively controls the presynaptic nanoscale organisation of reserve synaptic vesicles

Abstract Neurotransmitter release relies on the regulated fusion of synaptic vesicles (SVs) that are tightly packed within the presynaptic bouton of neurons. The mechanism by which SVs are clustered at the presynapse, while preserving their ability to dynamically recycle to support neuronal communic...

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Bibliographic Details
Main Authors: Shanley F. Longfield, Rachel S. Gormal, Matis Feller, Pierre Parutto, Jürgen Reingruber, Tristan P. Wallis, Merja Joensuu, George J. Augustine, Ramón Martínez-Mármol, David Holcman, Frédéric A. Meunier
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46256-1
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