Towards an Accessible Hollow Fiber Infection Model - Performance of Polysulfone Hemodialyzer Compared to a Commercial Cartridge

BACKGROUND: The Hollow Fiber Infection Model (HFIM) is established for studying pharmacodynamic (PD) effects considering pharmacokinetic (PK) profiles. The core is a cartridge with bacteria retained outside hollow fibers, which nutrients, metabolites and anti-infectives can selectively permeate. How...

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Bibliographic Details
Main Authors: David Schrey, Miklas Martens, Niklas Kroemer, Christoph Pfaffendorf, Aneeq Farooq, Sebastian G. Wicha
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Global Antimicrobial Resistance
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524004144
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