Dual-color optical activation and suppression of neurons with high temporal precision

Dual-color optical activation and suppression of neurons with high temporal precision

A well-known phenomenon in the optogenetic toolbox is that all light-gated ion channels, including red-shifted channelrhodopsins (ChRs), are activated by blue light, whereas blue-shifted ChRs are minimally responsive to longer wavelengths. Here, we took advantage of this feature to create a system w...

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Bibliographic Details
Main Authors: Noëmie Mermet-Joret, Andrea Moreno, Agnieszka Zbela, Milad Nazari, Bárður Eyjólfsson Ellendersen, Raquel Comaposada Baro, Nathalie Krauth, Anne von Philipsborn, Andreas Toft Sørensen, Joaquin Piriz, John Yu-luen Lin, Sadegh Nabavi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
optogenetics
channelrhodopsin
mutagenesis
membrane channels
Online Access:https://elifesciences.org/articles/90327
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https://elifesciences.org/articles/90327

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