Piezo1 senses hyphae and initiates host defense against pathogenic fungi

Piezo1 senses hyphae and initiates host defense against pathogenic fungi

Summary: Candida albicans metamorphoses from benign yeast to a rigid hyphal, becoming an opportunistic pathogen in immunocompromised patients. The process by which immune cells discern fungal transformations remains elusive. Here, we report that the mechanosensitive ion channel Piezo1 is indispensab...

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Bibliographic Details
Main Authors: Yiran Shi, Bingying Yang, Yueyue Linghu, Yue Liu, Haoran Li, Yunzhi Xing, Binbin Wu, Yuting Gao, Liuqi Liao, Yi Zheng, Lei Pan, Xiufeng Sun, Qinghua Chen, Yongqiang Hou, Dongxue Su, Hongling Huang, Jiahuai Han, Shih-Chin Cheng, Dawang Zhou, Lanfen Chen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725006102
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http://www.sciencedirect.com/science/article/pii/S2211124725006102

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