Approaches and Challenges in Characterizing the Molecular Content of Extracellular Vesicles for Biomarker Discovery

Approaches and Challenges in Characterizing the Molecular Content of Extracellular Vesicles for Biomarker Discovery

Extracellular vesicles (EVs) are lipid bilayer nanoparticles released from all known cells and are involved in cell-to-cell communication via their molecular content. EVs have been found in all tissues and body fluids, carrying a variety of biomolecules, including DNA, RNA, proteins, metabolites, an...

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Bibliographic Details
Main Authors: Suman Kumari, Christopher Lausted, Kelsey Scherler, Alphonsus H. C. Ng, Yue Lu, Inyoul Lee, Leroy Hood, Kai Wang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomolecules
Subjects:
extracellular vesicles
EV biomarkers
EV RNA subtypes
RNA characterization
proteins characterization methods
single EV analysis
Online Access:https://www.mdpi.com/2218-273X/14/12/1599
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