SMR-guided molecular subtyping and machine learning model reveals novel prognostic biomarkers and therapeutic targets in non-small cell lung adenocarcinoma
Abstract Non-small cell lung adenocarcinoma (LUAD) is a markedly heterogeneous disease, with its underlying molecular mechanisms and prognosis prediction presenting ongoing challenges. In this study, we integrated data from multiple public datasets, including TCGA, GSE31210, and GSE13213, encompassi...
Saved in:
Main Authors: | Baozhen Wang, Yichen Yin, Anqi Wang, Weidi Liu, Jing Chen, Tao Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-85471-8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Unraveling disulfidptosis for prognostic modeling and personalized treatment strategies in lung adenocarcinoma
by: Xiangyu Xu, et al.
Published: (2024-12-01) -
Chromatin accessibility reveals potential prognostic value of the peak set associated with smoking history in patients with lung adenocarcinoma
by: Han Liang, et al.
Published: (2024-12-01) -
Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma
by: Miaodong Wang, et al.
Published: (2025-01-01) -
Investigating lung cancer microenvironment from cell segmentation of pathological image and its application in prognostic stratification
by: Xu Zhang, et al.
Published: (2025-01-01) -
Multi-omics characterization and machine learning of lung adenocarcinoma molecular subtypes to guide precise chemotherapy and immunotherapy
by: Yi Zhang, et al.
Published: (2024-11-01)