Identification of cell-type-specific, transcriptionally active transposable elements using long-read RNA-sequencing data-based comprehensive annotation

Identification of cell-type-specific, transcriptionally active transposable elements using long-read RNA-sequencing data-based comprehensive annotation

Abstract Background The biological functions of transposable element (TE)-derived transcripts during physiological development, disease development, and progression have been previously reported. However, research on locus-specific TE-derived transcript expression in various human cell types remains...

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Bibliographic Details
Main Authors: Chaemin Lim, Hyunsu An, Jihwan Park
Format: Article
Language:English
Published: BioMed Central 2025-08-01
Series:Genomics & Informatics
Subjects:
Single-cell RNA-sequencing
Long-read RNA-sequencing
Transposable element
Transcriptome annotation
De novo transcript
Online Access:https://doi.org/10.1186/s44342-025-00048-1
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https://doi.org/10.1186/s44342-025-00048-1

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