Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation

Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation

Abstract In this study, we investigated the cerebroprotective effects of fenchone (FEN) against brain ischemia through in silico and in vivo approaches, focusing on the inhibition of nitric oxide synthase (NOS) and the modulation of oxidative stress markers. Molecular docking revealed the potential...

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Bibliographic Details
Main Authors:	Bangaru Mamatha, Anka Rao Areti, DSNBK Prasanth, Narender Malothu
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2025-01-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	Fenchone Nitric oxide synthase BCCAO/R Cerebroprotective In silico studies
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100336&lng=en&tlng=en
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