GPX4 deficiency-induced ferroptosis drives endometrial epithelial fibrosis in polycystic ovary syndrome

GPX4 deficiency-induced ferroptosis drives endometrial epithelial fibrosis in polycystic ovary syndrome

The increased risk of infertility and endometrial lesions (such as endometrial hyperplasia or cancer) in polycystic ovary syndrome (PCOS) are closely associated with the lack of cyclical transformation in the endometrium. However, the underlying mechanisms remain incompletely understood. Though inte...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhenhong Ye, Ming Cheng, Weisi Lian, Yueqi Leng, Xunsi Qin, Yue Wang, Ping Zhou, Xiyao Liu, Tianliu Peng, Ruiqi Wang, Yilei He, Heng Pan, Yue Zhao, Rong Li
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
Subjects:
Polycystic ovary syndrome
Ferroptosis
Endometrial fibrosis
Organoid
Female infertility
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001284
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2213231725001284

Similar Items