Imaging tumor and ascites-associated macrophages in a mouse model of metastatic ovarian cancer

Imaging tumor and ascites-associated macrophages in a mouse model of metastatic ovarian cancer

Abstract Background Tumor-Associated Macrophages (TAMs) play a critical role in the pathogenesis and progression of ovarian cancer, a lethal gynecologic malignancy. [124I]iodo-DPA-713 is a PET radiotracer that is selectively trapped within reactive macrophages. We have employed this radioligand here...

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Bibliographic Details
Main Authors: Catherine A. Foss, Flonné Wildes, Delia Mezzanzanica, Franca Podo, Chien-Fu Hung, Santosh Yadav, Marie-France Penet Vidaver
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:EJNMMI Research
Subjects:
Macrophages
iodo-DPA-713
Ovarian cancer
TAMs
Ascites
ID8-Defb29-VEGF
Online Access:https://doi.org/10.1186/s13550-024-01157-8
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https://doi.org/10.1186/s13550-024-01157-8

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