Sex-based associations between neighborhood disadvantage and brain–gut alterations in individuals with irritable bowel syndrome

Sex-based associations between neighborhood disadvantage and brain–gut alterations in individuals with irritable bowel syndrome

Abstract Background Irritable bowel syndrome (IBS) is a stress-sensitive disorder that exhibits sex differences in brain–gut–microbiome interactions. Neighborhood disadvantage is a chronic stressor that may influence brain–gut–microbiome health in patients with IBS, potentially contributing to clini...

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Bibliographic Details
Main Authors: Lisa A. Kilpatrick, Lin Chang, Jennifer S. Labus, Andrea S. Shin, Michelle Choy, Tien S. Dong, Bruce Naliboff, Emeran A. Mayer, Arpana Church
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Biology of Sex Differences
Subjects:
Irritable bowel syndrome
Sex-differences
Brain–gut–microbiome interactions
Prevotella
Area deprivation index
Online Access:https://doi.org/10.1186/s13293-025-00739-y
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https://doi.org/10.1186/s13293-025-00739-y

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