Glycosylation of ceramide synthase 6 is required for its activity
Sphingolipids play key roles in membrane structure and cellular signaling. Ceramide synthase (CerS)-generated ceramide is implicated in cellular stress responses and induction of apoptosis. Ceramide and other sphingolipids are linked to the induction of ER stress response pathways. However, the mech...
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Main Authors: | Alexandra J. Straus, Grace Mavodza, Can E. Senkal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227524002207 |
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