Mechanical Stretch Control of Adipocyte AKT Signaling and the Role of FAK and ROCK Mechanosensors

Mechanical Stretch Control of Adipocyte AKT Signaling and the Role of FAK and ROCK Mechanosensors

Adipose tissue in vivo is physiologically exposed to compound mechanical loading due to bodyweight bearing, posture, and motion. The capability of adipocytes to sense and respond to mechanical loading milieus to influence metabolic functions may provide a new insight into obesity and metabolic disea...

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Bibliographic Details
Main Authors: Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Ruiguo Yang, Viswanathan Saraswathi, Jason K. Kim, Jung Yul Lim
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
adipocyte
mechanical stretch loading
insulin signaling
AKT
GLUT4
FAK
Online Access:https://www.mdpi.com/2306-5354/11/12/1279
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