Differential tumor protein expression at follicular lymphoma diagnosis reveals dysregulation of key molecular pathways associated with histological transformation

Differential tumor protein expression at follicular lymphoma diagnosis reveals dysregulation of key molecular pathways associated with histological transformation

Abstract Follicular lymphoma (FL) is the most common low-grade lymphoma. Despite its indolent nature, FL carries an inherent risk of histological transformation (HT) to a more aggressive lymphoma. Existing biomarkers are insufficient to predict HT, indicating the need for more robust biological pred...

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Main Authors: Marie Hairing Enemark, Katharina Wolter, Trine Engelbrecht Hybel, Maja Dam Andersen, Emma Frasez Sørensen, Linnea Meier Hindkaer, Kristina Lystlund Lauridsen, Charlotte Madsen, Trine Lindhardt Plesner, Stephen Hamilton-Dutoit, Bent Honoré, Maja Ludvigsen
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Follicular lymphoma
Histological transformation
Proteomics
Online Access:https://doi.org/10.1038/s41598-024-81693-4
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https://doi.org/10.1038/s41598-024-81693-4

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