The impact of 9-azaglycophymine and phenylguanidine derivatives on the proliferation of various breast cancer cell lines in vitro and in vivo
Abstract Quinazolinones, particularly 9-azaglycophymines, and closely related derivatives and precursors were tested in vitro against various breast cancer cell lines representing the major types of breast tumors. Among the 49 compounds tested, azaglycophymine derivative 19 with an electron-withdraw...
Saved in:
| Main Authors: | Ibrahim Morgan, Robert Rennert, Robert Berger, Sanja Jelača, Danijela Maksimović-Ivanić, Duško Dunđerović, Sanja Mijatović, Goran N. Kaluđerović, Ludger A. Wessjohann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-71624-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis and Structural Characterization of Novel 2-Aminomethyl Quinazolin-4(3H)-ones as Organic Building Blocks
by: Feyzi Sinan Tokalı
Published: (2022-12-01) -
Organic Moiety on Sn(IV) Does Matter for In Vitro Mode of Action: <i>n</i>Bu<sub>3</sub>Sn(IV) Compounds with Carboxylato <i>N</i>-Functionalized 2-Quinolones Induce Anoikis-like Cell Death in A375 Cells
by: Marijana P. Kasalović, et al.
Published: (2024-11-01) -
Synthesis, biological evaluations, and in silico assessments of phenylamino quinazolinones as tyrosinase inhibitors
by: Sara Moghadam Farid, et al.
Published: (2025-01-01) -
Quinazolinone Derivative MR2938 Protects DSS-Induced Barrier Dysfunction in Mice Through Regulating Gut Microbiota
by: Ling Lv, et al.
Published: (2025-01-01) -
Synthesis of bioactive quinazolin-4(3H)-one derivatives via microwave activation tailored by phase-transfer catalysis
by: El-Badry Yaser A., et al.
Published: (2020-06-01)