A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis

A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis

The efficacy of many compounds against Mycobacterium tuberculosis is often limited when administered via conventional oral or injection routes due to suboptimal pharmacokinetic characteristics. Inhalation-based delivery methods have been investigated to achieve high local therapeutic doses in the lu...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xirong Tian, Yamin Gao, Chunyu Li, Wanli Ma, Jingran Zhang, Yanan Ju, Jie Ding, Sanshan Zeng, H. M. Adnan Hameed, Htin Lin Aung, Nanshan Zhong, Gregory M. Cook, Jinxing Hu, Tianyu Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	inhalation administration autoluminescence tuberculosis murine model chemotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1400436/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Influence of Ferronickel Slag on Impermeability of Seawater-Corroded Cement Soil Using an Electrochemical Test
by: Sanshan Chen, et al.
Published: (2022-01-01)

Strategies for preventing and managing osteoporosis in elderly breast cancer patients undergoing aromatase inhibitor therapy
by: Andi Tian, et al.
Published: (2025-01-01)

Application Design of AI Image Recognition in Power System
by: Boyan Jia, et al.
Published: (2021-01-01)

Application of AI Image Recognition in the Omnidirectional Monitoring System for Power Transmission Lines
by: Siming Zeng, et al.
Published: (2021-01-01)

Description and Dynamic Analyses of the 1935 Luchedu Rock Avalanche in Sichuan, China
by: Jie Cui, et al.
Published: (2022-01-01)

Anterior cervical endoscopic release and reduction, posterior instrumentation and fusion for irreducible atlantoaxial dislocation: A technical note
by: Kai Zhang, et al.
Published: (2025-02-01)

Characteristics of Pavement Cement Concrete Incorporating Steel Slag Powder
by: Erbu Tian, et al.
Published: (2022-01-01)

Efficient Parallel Implementation of Active Appearance Model Fitting Algorithm on GPU
by: Jinwei Wang, et al.
Published: (2014-01-01)

Effects of proprioceptive training in the recovery of patients submitted to meniscus surgery: systematic review and meta-analysis
by: Song Jin, et al.
Published: (2022-06-01)

Association of breast milk microbiota and metabolites with neonatal jaundice
by: TianYu Liu, et al.
Published: (2025-01-01)

A Review on Structural Development of Magnetorheological Fluid Damper
by: Xianju Yuan, et al.
Published: (2019-01-01)

Failure characteristics of overlying strata and mechanism of strong ground pressure during the large‐scale and continuous mining of deep multi working faces
by: Defei Zhang, et al.
Published: (2024-11-01)

BLSENet: A Novel Lightweight Bilinear Convolutional Neural Network Based on Attention Mechanism and Feature Fusion Strategy for Apple Leaf Disease Classification
by: Tianyu Fang, et al.
Published: (2024-01-01)

A survey of key protocol and application scenario of time-sensitive network
by: Peizhuang CONG, et al.
Published: (2019-10-01)

Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke
by: SUN Jie, et al.
Published: (2022-10-01)

Analytical Solution for Consolidation of Vertical Drains-Impervious Piles with Multiple Composite Foundations under Nonuniform Initial Pore Pressure and Time-Dependent Well Resistance
by: Yuguo Zhang, et al.
Published: (2022-01-01)

Analysis of China's Telecommunication Business Strategies Based on Porter's Five-Force Model on 4G Era
by: Yonghui Zhang, et al.
Published: (2014-04-01)

Last digit tendency: Lucky numbers and psychological rounding in mobile transactions
by: Hai Wang, et al.
Published: (2025-01-01)

METHOD OF FIRST-ORDER APPROXIMATIONS OF INTER FORCE FOR STRUCTURAL TOPOLOGY OPTIMIZATION WITH STRESS CONSTRAINTS
by: PENG XiRong, et al.
Published: (2016-01-01)

Association of serum chloride levels with all-cause mortality among patients in surgical intensive care units: a retrospective analysis of the MIMIC-IV database
by: Quan Ma, et al.
Published: (2025-01-01)

Comparative Analysis of Visual Performance and Astigmatism Tolerance with Monofocal, Bifocal, and Extended Depth-of-Focus Intraocular Lenses Targeting Slight Myopia
by: Jie Xu, et al.
Published: (2020-01-01)

Effect of Suspension Massage Exercise Technique on Cervicogenic Insomnia and Vertebrobasilar Artery Hemodynamics
by: ZHANG Tianyu, et al.
Published: (2023-10-01)

ApoB/ApoA-Ι is associated with major cardiovascular events and readmission risk of patients after percutaneous coronary intervention in one year
by: Jie Zhang, et al.
Published: (2025-01-01)

Health economics assessment of statin therapy initiation thresholds for atherosclerosis prevention in China: a cost-effectiveness analysis
by: Tianyu Feng, et al.
Published: (2025-01-01)

Permanence and Global Attractivity of a Discrete Logistic Model with Impulses
by: Chunyu Gao, et al.
Published: (2013-01-01)

STUDY ON THE EQUIVALENCE RELATION BETWEEN THE ACCELERATED CORROSION OF SALT SPRAY AND THE COASTAL ATMOSPHERIC ENVIRONMENT
by: ZANG TianYu, et al.
Published: (2018-01-01)

Research on named entity recognition method in cybersecurity based on soft prompt tuning and reinforcement learning
by: TIAN Zeshu, et al.
Published: (2024-10-01)

Exposure to PM2.5 and its components leads to obesity: role of socioeconomic status
by: Yindi Peng, et al.
Published: (2025-01-01)

Main Shaft Seal Leakage Fault Analysis and Treatment Methods for Vertical Hydraulic Turbine Unit
by: SHANG Tianyu
Published: (2023-01-01)

Multi-Scale Channel Distillation Network for Image Compressive Sensing
by: Tianyu Zhang, et al.
Published: (2025-01-01)

Dynamic Stiffness Formulation for Free Vibration of Truncated Conical Shell and Its Combinations with Uniform Boundary Restraints
by: Chunyu Zhang, et al.
Published: (2021-01-01)

Fast-flucos:malicious domain name detection method for Fast-flux based on DNS traffic
by: Chunyu HAN, et al.
Published: (2020-05-01)

Dynamic Coupling Analysis of Vehicle-Bridge System for Long-Span Suspension Bridge Based on Backpropagation Neural Network Method
by: Zuolong Luo, et al.
Published: (2020-01-01)

Event-Based User Classification in Weibo Media
by: Liang Guo, et al.
Published: (2014-01-01)

Patients’ Educational Program Could Improve Azathioprine Adherence in Crohn’s Disease Maintenance Therapy
by: Lei Wang, et al.
Published: (2020-01-01)

Analytical and Numerical Study of the Ground Pressure of the Work Face Crossing the Fault
by: Yanan Gao, et al.
Published: (2021-01-01)

Distributed optimization and scheduling strategy for source load storage distribution grid based on alliance chain
by: Jinhua Tian, et al.
Published: (2024-08-01)

Associations between cardiovascular-kidney-metabolic syndrome and disability in activities of daily living: a nationwide longitudinal study among the middle-aged and older adults in China
by: Junfeng Zhang, et al.
Published: (2025-01-01)

Video description method based on multidimensional and multimodal information
by: Enjie DING, et al.
Published: (2020-02-01)

ENGLISH WITH INDONESIA TASTE DOMINANT CULTURE SHIFT TO LOCAL CULTURE
by: Moh. Yamin
Published: (2017-05-01)