Naringenin as a neurotherapeutic agent in Alzheimer’s disease: epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

Naringenin as a neurotherapeutic agent in Alzheimer’s disease: epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

Alzheimer’s disease (AD) remains a major neurodegenerative disorder characterized by progressive cognitive decline, amyloid-β (Aβ) aggregation, tau pathology, oxidative stress, and chronic neuroinflammation. In recent years, the dietary flavonoid naringenin, abundant in citrus fruits, has gained att...

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Bibliographic Details
Main Authors: Zhenzhen Lai, Long Ke, Wei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
naringenin
Alzheimer’s disease
epigenetic
gut microbiota
molecular neuroprotection
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1647967/full
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