Pericyte pannexin1 controls cerebral capillary diameter and supports memory function

Abstract In the blood-brain-barrier, contractile pericytes fine-tune the capillary resistance and blood supply to meet neuro-metabolic demands; molecular players governing these functions remain unclear. Here we show that mice cerebral pericytes express functional pannexin1 (Panx1) channels, which d...

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Bibliographic Details
Main Authors: Sandra Mai-Morente, Eugenia Isasi, Alberto Rafael, Gonzalo Budelli, Silvia Olivera-Bravo, Nathalia Vitureira, Verónica Abudara
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61312-0
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