Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction

Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction

Polymeric scaffolds are promising in tissue engineering due to their structural similarity to extracellular matrix components. This study aimed to design freeze-dried hydrogels based on chitosan (CHT) and hyaluronic acid (HA). Chitosan-based gels were crosslinked with oxidized maltodextrin (MDo) bef...

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Bibliographic Details
Main Authors: Salim Hamidi, Mickael Maton, Feng Hildebrand, Valérie Gaucher, Cédric Bossard, Frédéric Cazaux, Jean Noel Staelens, Nicolas Blanchemain, Bernard Martel
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
polymeric scaffolds
chitosan
hyaluronic acid
crosslinking hydrogels
cartilage tissue engineering
porous morphology
Online Access:https://www.mdpi.com/1420-3049/30/10/2202
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