Testing organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

Cystic Fibrosis (CF) is a life-shortening disease that is caused by mutations in the CFTR gene, a gene that is expressed in multiple organs. There are several primary tissue models of CF disease, including nasal epithelial cultures and rectal organoids, that are effective in reporting the potential...

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Bibliographic Details
Main Authors: Abdelkader Daoud, Sunny Xia, Onofrio Laselva, Janet Jiang, Christine E. Bear
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Stem Cell Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1873506125000030
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