The effect of caffeine dose on caffeine and paraxanthine changes in serum and saliva and CYP1A2 enzyme activity in athletes: a randomized placebo-controlled crossover trial

Abstract Background Although caffeine (CAF) supplementation has been shown to improve exercise performance, its dose-dependent effect on CAF metabolism has not been sufficiently investigated. The aim of this study was to evaluate the effects of 3, 6 and 9 mg of CAF/kgBM on changes of CAF and paraxan...

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Main Authors: Natalia Główka, Jakub Malik, Jacek Anioła, Emilia E. Zawieja, Agata Chmurzynska, Krzysztof Durkalec-Michalski
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Nutrition & Metabolism
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Online Access:https://doi.org/10.1186/s12986-024-00863-3
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