Endothelial dysfunction prognostic role in cardiovascular pathology
Endothelial dysfunction (ED) amplifies the effects of vascular risk factors (RF), and is directly linked to pathogenetic mechanisms of atherosclerosis and its complications. To clarify ED prognostic role, a review of relevant studies was performed. ED interrelation with various clinical outcomes of...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2008-10-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1296 |
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| _version_ | 1849342369868021760 |
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| author | T. S. Romanenko M. G. Omelyanenko A. V. Kontsevaya |
| author_facet | T. S. Romanenko M. G. Omelyanenko A. V. Kontsevaya |
| author_sort | T. S. Romanenko |
| collection | DOAJ |
| description | Endothelial dysfunction (ED) amplifies the effects of vascular risk factors (RF), and is directly linked to pathogenetic mechanisms of atherosclerosis and its complications. To clarify ED prognostic role, a review of relevant studies was performed. ED interrelation with various clinical outcomes of cardiovascular disease (CVD) was demonstrated. At the moment, the main method of 5-10-year CVD risk assessment in CVD patients and asymptomatic individuals is evaluation of total mortality risk. ED could be an independent marker of atherosclerosis, including its subclinica course, and a predictor of various CVD events. Endothelium may link various RF and their damaging effect on vascular wall. Future studies will confirm whether endothelial function assessment could be used for dynamic follow-up of CVD patients, as a measure of prevention effectiveness. |
| format | Article |
| id | doaj-art-2e836df3c4f5468e8c6c8bda4035f6e5 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2008-10-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2e836df3c4f5468e8c6c8bda4035f6e52025-08-20T03:43:26Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-10-01751161211006Endothelial dysfunction prognostic role in cardiovascular pathologyT. S. Romanenko0M. G. Omelyanenko1A. V. Kontsevaya2Ivanovo State Medical Academy, IvanovoIvanovo State Medical Academy, IvanovoState Research Center for Preventive Medicine, MoscowEndothelial dysfunction (ED) amplifies the effects of vascular risk factors (RF), and is directly linked to pathogenetic mechanisms of atherosclerosis and its complications. To clarify ED prognostic role, a review of relevant studies was performed. ED interrelation with various clinical outcomes of cardiovascular disease (CVD) was demonstrated. At the moment, the main method of 5-10-year CVD risk assessment in CVD patients and asymptomatic individuals is evaluation of total mortality risk. ED could be an independent marker of atherosclerosis, including its subclinica course, and a predictor of various CVD events. Endothelium may link various RF and their damaging effect on vascular wall. Future studies will confirm whether endothelial function assessment could be used for dynamic follow-up of CVD patients, as a measure of prevention effectiveness.https://cardiovascular.elpub.ru/jour/article/view/1296endothelial dysfunctioncardiovascular diseaserisk assessment |
| spellingShingle | T. S. Romanenko M. G. Omelyanenko A. V. Kontsevaya Endothelial dysfunction prognostic role in cardiovascular pathology Кардиоваскулярная терапия и профилактика endothelial dysfunction cardiovascular disease risk assessment |
| title | Endothelial dysfunction prognostic role in cardiovascular pathology |
| title_full | Endothelial dysfunction prognostic role in cardiovascular pathology |
| title_fullStr | Endothelial dysfunction prognostic role in cardiovascular pathology |
| title_full_unstemmed | Endothelial dysfunction prognostic role in cardiovascular pathology |
| title_short | Endothelial dysfunction prognostic role in cardiovascular pathology |
| title_sort | endothelial dysfunction prognostic role in cardiovascular pathology |
| topic | endothelial dysfunction cardiovascular disease risk assessment |
| url | https://cardiovascular.elpub.ru/jour/article/view/1296 |
| work_keys_str_mv | AT tsromanenko endothelialdysfunctionprognosticroleincardiovascularpathology AT mgomelyanenko endothelialdysfunctionprognosticroleincardiovascularpathology AT avkontsevaya endothelialdysfunctionprognosticroleincardiovascularpathology |