Role of DPP-4 and NPY Family Peptides in Gastrointestinal Symptoms Associated with Obesity and Type 2 Diabetes Mellitus

Role of DPP-4 and NPY Family Peptides in Gastrointestinal Symptoms Associated with Obesity and Type 2 Diabetes Mellitus

<i>Background and Objectives</i>: Neuropeptide Y (NPY) family peptides and dipeptidyl peptidase-4 (DPP-4) are involved in gastrointestinal regulation and may contribute to obesity and type 2 diabetes mellitus (T2DM) pathophysiology. This study investigates their expression in jejunal mus...

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Bibliographic Details
Main Authors: Mantas Malinauskas, Deimante Paskeviciene, Rūta Steponaitienė, Rita Gudaityte, Limas Kupčinskas, Anna Casselbrant, Almantas Maleckas
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Medicina
Subjects:
dipeptidyl peptidase-4
obesity
type 2 diabetes
neuropeptide Y
peptide YY
pancreatic polypeptide
Online Access:https://www.mdpi.com/1648-9144/61/3/504
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