Distinct transcription kinetics of pluripotent cell states

Distinct transcription kinetics of pluripotent cell states

Abstract Mouse embryonic stem cells (mESCs) can adopt naïve, ground, and paused pluripotent states that give rise to unique transcriptomes. Here, we use transient transcriptome sequencing (TT‐seq) to define both coding and non‐coding transcription units (TUs) in these three pluripotent states and co...

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Bibliographic Details
Main Authors: Rui Shao, Banushree Kumar, Katja Lidschreiber, Michael Lidschreiber, Patrick Cramer, Simon J Elsässer
Format: Article
Language:English
Published: Springer Nature 2022-01-01
Series:Molecular Systems Biology
Subjects:
mouse pluripotent stem cells
transcription termination
transcription unit annotation
transcription velocity
transient transcriptome sequencing
Online Access:https://doi.org/10.15252/msb.202110407
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https://doi.org/10.15252/msb.202110407

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