Allosteric modulation of serotonin and dopamine transporters: New insights from computations and experiments

Human monoamine transporters (MATs) are critical to regulating monoaminergic neurotransmission by translocating their substrates from the synaptic space back into the presynaptic neurons. As such, their primary substrate binding site S1 has been targeted by a wide range of compounds for treating neu...

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Bibliographic Details
Main Authors: Hoang Nguyen, Mary Hongying Cheng, Ji Young Lee, Shaili Aggarwal, Ole Valente Mortensen, Ivet Bahar
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Physiology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2665944124000099
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