Identification of hub genes and immune-related pathways in acute myeloid leukemia: insights from bioinformatics and experimental validation

Identification of hub genes and immune-related pathways in acute myeloid leukemia: insights from bioinformatics and experimental validation

BackgroundThis study aims to identify the hub genes and immune-related pathways in acute myeloid leukemia (AML) to provide new theories for immunotherapy.MethodsWe use bioinformatics methods to find and verify the hub gene. At the same time, we use the results of GSEA enrichment analysis to find imm...

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Bibliographic Details
Main Authors: Mingliang Shan, Li Xu, Wenzhe Yang, Shiguo Liu, Zhaoqing Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
AML
hub gene
bioinformatics
machine learning
Mendelian randomization
plasmid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1511824/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1511824/full

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