Intraindividual variability of von Willebrand factor and the need for repeated testing

Background: Diagnosing von Willebrand disease (VWD) is complicated by intraindividual variation of von Willebrand factor (VWF). Current guidelines define VWD as VWF antigen (VWF:Ag) or VWF activity of <0.30 or <0.50 × 103 IU/L depending on the presence of bleeding symptoms. However, there is n...

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Bibliographic Details
Main Authors: Malene Helligsø Kirkeby, Johanne Andersen Højbjerg, Anders Mønsted Abildgaard, Julie Brogaard Larsen
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Research and Practice in Thrombosis and Haemostasis
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Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925002134
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