Targeting steroid receptor coactivators in cancer via small molecule agents

Steroid receptor coactivators (SRCs) are a family of nuclear receptor (NR) coregulators comprised of three evolutionarily related, yet distinct proteins SRC-1, SRC-2 and SRC-3. The SRCs interact with NRs and other transcription factors to regulate their transcriptional activity, impacting a wide var...

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Bibliographic Details
Main Authors: Yosi Gilad, Ortal Shimon, David M. Lonard, Bert W. O’Malley
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Drug Discovery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2024.1514412/full
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