The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.

Nosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial pathogens that are well adapted to surviving and proliferating in this setting, aft...

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Main Authors: Glen P Carter, Gillian R Douce, Revathi Govind, Pauline M Howarth, Kate E Mackin, Janice Spencer, Anthony M Buckley, Ana Antunes, Despina Kotsanas, Grant A Jenkin, Bruno Dupuy, Julian I Rood, Dena Lyras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002317&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002317&type=printable

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