Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration

Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration

Abstract Background Intervertebral disc degeneration (IDD) is a progressive age‐related disorder characterized by the reduction in the number of nucleus pulposus cells (NPCs) and degradation of extracellular matrix (ECM), thereby leading to chronic pain and disability. The pathogenesis of IDD is mul...

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Bibliographic Details
Main Authors:	Hong Sun, Jiajie Guo, Zhilin Xiong, Yong Zhuang, Xu Ning, Miao Liu
Format:	Article
Language:	English
Published:	Wiley 2024-12-01
Series:	JOR Spine
Subjects:	cell therapy intervertebral disc degeneration nucleus pulposus cells programmed cell death traditional Chinese medicine
Online Access:	https://doi.org/10.1002/jsp2.70011
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