A dynamical model of the spindle position checkpoint

A dynamical model of the spindle position checkpoint

Abstract The orientation of the mitotic spindle with respect to the polarity axis is crucial for the accuracy of asymmetric cell division. In budding yeast, a surveillance mechanism called the spindle position checkpoint (SPOC) prevents exit from mitosis when the mitotic spindle fails to align along...

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Bibliographic Details
Main Authors: Ayse Koca Caydasi, Maiko Lohel, Gerd Grünert, Peter Dittrich, Gislene Pereira, Bashar Ibrahim
Format: Article
Language:English
Published: Springer Nature 2012-05-01
Series:Molecular Systems Biology
Subjects:
Bfa1
mitotic exit network
modeling and simulation
spindle position checkpoint
Tem1
Online Access:https://doi.org/10.1038/msb.2012.15
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https://doi.org/10.1038/msb.2012.15

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