Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection.

Host protection from fungal infection is thought to ensue in part from the activity of Syk-coupled C-type lectin receptors and MyD88-coupled toll-like receptors in myeloid cells, including neutrophils, macrophages and dendritic cells (DCs). Given the multitude of cell types and receptors involved, e...

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Bibliographic Details
Main Authors: Paul G Whitney, Eva Bär, Fabiola Osorio, Neil C Rogers, Barbara U Schraml, Safia Deddouche, Salomé LeibundGut-Landmann, Caetano Reis e Sousa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004276
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