A Hierarchical Core-Shell Structure of NiO@Cu<sub>2</sub>O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection

Non-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core–shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)<sub>2</sub>@Cu(OH)<sub>2</sub>-CF) w...

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Bibliographic Details
Main Authors: Yueyun Huang, Jiahua You, Yingru Ding, Yun Xie, Ting Wang, Fanglong Zhu, Weiping Gong, Zhenting Zhao
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/15/1/47
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Summary:Non-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core–shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)<sub>2</sub>@Cu(OH)<sub>2</sub>-CF) was fabricated and derived from NiO@Cu<sub>2</sub>O-CF for glucose sensing. Cyclic voltammetry and amperometry experiments have demonstrated the efficient electrochemical catalysis of glucose under alkaline conditions. The measurement displays that the fabricated sensor exhibits a detection scale of 0.005–4.5 mM with a detection sensitivity of 4.67 µA/µM/cm<sup>2</sup>. It has remarkable response/recovery times in respect of 750 μM glucose (1.0 s/3.5 s). Moreover, the NiO@Cu<sub>2</sub>O-CF shows significant selectivity, reliable reproducibility and long-term stability for glucose determination, suggesting it is a suitable candidate for further applications.
ISSN:2079-4991