Comparative genomic analysis of resistance and virulence genes in staphylococcus epidermidis and their impact on clinical outcome of musculoskeletal infections

Comparative genomic analysis of resistance and virulence genes in staphylococcus epidermidis and their impact on clinical outcome of musculoskeletal infections

Abstract Staphylococcus epidermidis is an opportunistic commensal cutaneous biofilm-producing agent frequently causing musculoskeletal infections (MSI) with/without implants. This study was design to evaluate phenotypic and genomic relatedness between commensal skin and MSI S. epidermidis isolates a...

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Main Authors: Ingrid Nayara Marcelino Santos, Felipe Alberto-Lei, Fernanda Fernandes Santos, Mariana Felix Cerqueira Balera, Mariana Neri Kurihara, Carolina Coelho Cunha, Laís Sales Seriacopi, Thomas Stravinskas Durigon, Fernando Baldy Reis, Ana Karolina Antunes Eisen, Giovana Santos Caleiro, Jansen de Araújo, Edison Luiz Durigon, Giselle Burlamaqui Klautau, Mauro José Salles
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Coagulase-negative Staphylococci
Staphylococcus epidermidis
Biofilm production
Whole-genomic sequencing
Phylogeny
mecA gene
Online Access:https://doi.org/10.1038/s41598-025-09061-4
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