Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.

Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.

Following injury, dorsal root ganglion (DRG) neurons undergo transcriptional changes so as to adopt phenotypic changes that promote cell survival and axonal regeneration. Here we used a microarray approach to profile changes in a population of small noncoding RNAs known as microRNAs (miRNAs) in the...

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Bibliographic Details
Main Authors: Iain T Strickland, Louise Richards, Fiona E Holmes, David Wynick, James B Uney, Liang-Fong Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023423&type=printable
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