Application of seven tools for evaluation of greenness of chromatographic methods for Remdesivir analysis
Green analytical chemistry is concerned with making analytical techniques more secure and environmentally friendly. A crucial aspect of this approach is the assessment of the greenness of analytical methods. Remdesivir, a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor, has been authorized by...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Green Analytical Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772577424000582 |
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| Summary: | Green analytical chemistry is concerned with making analytical techniques more secure and environmentally friendly. A crucial aspect of this approach is the assessment of the greenness of analytical methods. Remdesivir, a SARS-CoV-2 nucleotide analog RNA polymerase inhibitor, has been authorized by USFDA as the initial course of therapy for hospitalized COVID-19 patients. The proposed study evaluates greenness of several reported chromatographic methods for estimation of Remdesivir using seven different tools namely ComplexGAPI, BAGI, AGREE, AGREEprep, AMGS, ChlorTox and RGBfast. |
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| ISSN: | 2772-5774 |