Structural insights into the potential binding sites of Cathepsin D using molecular modelling techniques
Abstract Alzheimer’s disease (AD) is the most prevalent type of dementia caused by the accumulation of amyloid beta (Aβ) peptides. The extracellular deposition of Aβ peptides in human AD brain causes neuronal death. Therefore, it has been found that Aβ peptide degradation is a possible therapeutic t...
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| Main Authors: | Subodh A. Kamble, Sagar S. Barale, Ali Abdulmawjood Mohammed, Sneha B. Paymal, Nitin M. Naik, Kailas D. Sonawane |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2024-04-01
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| Series: | Amino Acids |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00726-023-03367-1 |
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